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General Information
TreatmentStem Cell Transplant Program The following are treated using autologous, allogeneic, or cord blood stem cell transplants:
Alternative/Complementary Medicine The Integrative Medicine Service at Memorial Sloan-Kettering Cancer Center complements mainstream medical care and addresses the emotional, social, and spiritual needs of patients and families. The Service includes inpatient and outpatient clinical care, as well as research, education, and training. In addition, this Service provides unique access to otherwise unavailable information about over-the-counter products and their impact in the context of cancer care via our About Herbs database available at:www.mskcc.org/aboutherbs. Individual therapies include:
Clinical Trials Continually updated clinical trial information can be found at:www.mskcc.org/clinicaltrials. Patients may call 800.525.2225 for further information and to schedule appointments. Late Effects Clinic For more information about the program, or to make an appointment, patients can call the Long-Term Follow-Up Program at 212.639.8138 Cancer Prevention and ScreeningOur Cancer Prevention and Wellness Program is a comprehensive program designed for anyone interested in cancer prevention and well-being. We offer one-on-one consultation with a Wellness Specialist, who will discuss a patient's health, family history, and lifestyle, and then work with a patient to design a personal program tailored to your specific needs. This program includes referral to screening services, smoking cessation, and nutrition counseling. For appointments, patients can call 888.MSK.WELL. For further information, visit our web site at: www.mskcc.org/wellness. Smoking Cessation We offer smoking cessation programs for those who have cancer, as well as for those who never did, through the Cancer Prevention and Wellness Program. They can be reached at 888.MSK.WELL. Our Counseling Center offers a smoking cessation program for cancer patients. They can be reached at 212.610.0507. Our web site, www.mskcc.org/smokingcessation, provides smoking cessation tips and a lung cancer risk assessment calculator for smokers and ex-smokers over the age of 50. Screening Be SMART! provides mobile breast cancer screening services for corporations, churches, and community groups in the New York metropolitan area. Memorial Sloan-Kettering Guttman Diagnostic Center provides breast cancer screening, and offers both women and men prevention and early detection services for gynecologic, prostate, and skin cancers. Throughout the year we provide free PSA, Head & Neck, and Skin Cancer screenings. Our Cancer Prevention and Wellness program hosts free cooking demonstrations. Support ServicesMemorial Sloan-Kettering offers survivorship and support services throughout the continuum of care. Our Counseling Center and Psychiatry Service offer individual, family, and group counseling for both outpatients and inpatients and their families. Specialized programs include art and music therapy. This Center also offers bereavement groups. In addition, a social worker is assigned to each patient floor and is available to patients, their families, and friends for help in dealing with the problems associated with a cancer diagnosis. Social workers provide counseling on adapting to serious illness, help communicating with family and friends—including young children—and offer assistance with the impact of illness on employment. Social workers also have information about community-based programs that assist with practical needs such as transportation for treatment and home-care costs. For patients who have completed treatment, our Post-Treatment Resources Program provides individual, family, and group counseling services, seminars and workshops, a telephone information helpline, and a lending/reference library. This program also helps patients with practical issues surrounding employment, insurance, quality of life, family life, etc. Supportive CarePain Service Home Care/Hospice Service Nutrition Service Rehabilitation Service Cooperative Group Membership
Clinical and Research EffortsDynamic collaborations among our basic researchers and clinicians, coupled with powerful new technologies, allow us to advance the biological understanding of cancer and to seek strategies to prevent, control, and hopefully cure cancer in the future. Adult Oncology Program For the year 2005—Number of oncologists includes all hospital attending staff: surgical oncologists, medical oncologists, radiation oncologists, neuro-oncologists, radiologists, pathologists, psycho-oncologists, and anesthesiologists, all of whom only treat cancer.
Memorial Sloan-Kettering Cancer Center
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General Information |
800.525.2225 |
Referring Physician Line |
212.639.5954 – Pediatric Department |
Location |
New York, New York |
Physical Plant |
Memorial Sloan-Kettering Cancer Center operates a Pediatric Day Hospital where children can receive intensive chemotherapy, transfusions, and other types of treatment and supportive care, all without having to stay overnight. If a child has to stay in the hospital, one parent can stay overnight in the child’s room, and there is a 24-hour visitation policy. |
Travel Assistance |
Memorial Sloan-Kettering Cancer Center helps coordinate transportation and participates in the “Corporate Angels.” This not-for-profit organization provides free plane transportation for cancer patients going to/from recognized cancer treatment centers. |
Lodging |
Social workers assist in lodging arrangements for families. A Ronald McDonald House across town is served by shuttle bus. |
Social Support |
The Social Work Department, psychiatrists, and psychologists work together to ensure that all children treated, as well as their siblings, receive help in adjusting to the emotional stresses of cancer. A staff of full-time teachers provides academic continuity with the child’s home classroom teachers to reduce the impact of treatment or days in the hospital on each child’s education. Child Life workers in the Pediatric Recreation Program also assist children in understanding and coping with the hospital experience. |
Home Health Care |
Memorial Sloan-Kettering Cancer Center arranges home health care for pediatric oncology patients. |
Ages Treated |
Children of all ages are treated. |
Chairman, Department of Pediatrics & Chief, Bone Marrow Transplant Service |
Richard J. O’Reilly, MD |
Director, Pediatric Day Hospital |
Farid Boulad, MD |
Operates Multidisciplinary Teams |
Each child treated at Memorial Sloan-Kettering Cancer Center has a tightly woven medical team, including an attending physician, a nurse practitioner, and a social worker. The attending physician makes the diagnosis, suggests the treatment strategy to the family, and supervises all aspects of care. The nurse practitioner provides continuity to the child and family throughout the course of treatment, coordinates the supportive care needs of the child during therapy, and fosters meaningful communication among the medical team and the child and family. The social worker provides practical and emotional support to the child and family to assist them with the stress of illness and its treatment and to help them to recruit many helpful supportive programs and resources within the community. |
Cooperative Group Membership |
Children’s Oncology Group (COG) |
Activities in Cooperative Group |
Participation in COG committees includes:
Oncologists are Principal Investigators on numerous studies. |
Average Number of Pediatric Clinical Trials |
62 |
Pediatric Clinical Trial Coordinator |
Elizabeth DeKosko—212.639.5962 |
The program of clinical and laboratory research in Pediatric Oncology is focused on a number of vital issues in the treatment of pediatric malignancies. Research studies are being conducted in the following areas:
The dominant theme of the Bone Marrow Transplantation biology research program has been the pursuit of effective strategies for the transplantation of patients lacking an HLA-matched sibling donor. Memorial has introduced the use of HLA-haplotype disparate T-cell–depleted marrow transplants for the treatment of children with SCID lacking a donor, an approach which, at our own and many other centers, has led to long-term survival with immunologic reconstitution and without GvHD for over 70 percent of patients transplanted. A major accomplishment of our program over the last eight years has been the definition of the biological factors contributing to graft failures complicating transplants of T-cell–depleted HLA-matched or HLA-disparate marrow in patients with leukemia.
Acute Leukemias & Lymphomas
Memorial Sloan-Kettering Cancer Center is a world leader in the treatment of acute leukemias and lymphomas. Treatment regimens developed at Memorial Sloan-Kettering Cancer Center are now the standard for high-risk forms of leukemia, achieving cure rates now approaching over 80 percent. Also, the Center performs allogeneic bone marrow transplants for early relapsed and 2+ remission. Additionally, Adoptive Cell Therapy with Immune T-cell treatment is used.
Bone Marrow Transplants
Memorial Sloan-Kettering Cancer Center performs bone marrow transplants and peripheral blood stem cell transplants following high dose chemotherapy. Transplants may use cord blood, or be HLA, A, B, D disparate, T-cell–depleted related, or unrelated unmodified and T-cell–depleted. Memorial Sloan-Kettering Cancer Center pioneered techniques for modifying a marrow graft so as to permit transplantation in children using blood-forming cells from their normal half-matched parents.
Brain tumors
Brain tumors are treated in two ways: 1) novel dose-intensive regimen with autologous peripheral stem cell rescue, and 2) chemotherapy regimes for germ cell tumors that do not require radiation.
Ewing’s Sarcoma/PNET
Treatments include: 1) improved dose-intensive chemotherapy regimes for high-risk disease, and 2) autologous PBSC transplants post-myeloablation for metastatic and relapsed disease.
Late Effects
Memorial Sloan-Kettering Cancer Center has developed a team of physicians, nurses, psychiatrists, neuro-psychologists, and social workers who have special expertise and experience dealing with the long-term consequences of cancer and its treatment in children. They have developed special programs to maximize each child’s normal growth and development after completion of treatment, to prevent or treat medical problems that may arise long after therapy, and to maximize a child’s adjustment and success in school, at work or play, and with the family at home.
Neuroblastoma
Memorial Sloan-Kettering Cancer Center offers improved dose-intensive chemotherapy with adjunctive use of 131 GD-2 specific antibodies for treatment of stage IV disease.
Osteogenic Sarcoma
Special treatment of osteogenic sarcomas includes high-dose chemotherapy with limb-sparing surgery. Memorial Sloan-Kettering Cancer Center pioneered the development of advanced surgical techniques, including limb-sparing surgery, which have not only improved long-term prognosis but also maximized the child’s chances for a normally functional life.
Retinoblastoma
Treatment involves a chemotherapy and laser surgery regimen, which bypasses the need for radiation.
Percent of children treated in each age range
Age Range |
0–1 |
2–5 |
6–12 |
13+ |
Percent Treated |
5% |
25% |
25% |
45% |
Pediatric Oncology Program, 2002
No. of Inpatient Beds |
No. of Admissions |
Average Length of Stay(days) |
No. of New Outpatients |
Total Outpatient Visits |
No. of Bone Marrow Transplants |
No. of Oncologists |
38 |
1,420 |
7.7 |
589 |
20,418 |
56 |
18 |
Because of the hereditary nature of a significant proportion of common cancers, genetic counseling and testing options are now viewed as an important part of oncologic care at specialty centers such as Memorial Sloan-Kettering Cancer Center (MSKCC). The Clinical Genetics Service in the Department of Medicine MSKCC offers genetic counseling, diagnostic referrals, and education regarding cancer risk to individuals and to families. The service is staffed by physicians specialized in cancer genetics and genetic counselors. As a part of a multidisciplinary approach to genetic counseling, families also have access to the services of nutritionists, psychiatrists, and social workers. Individualized guidelines for cancer-screening programs appropriate for a particular person's level of risk are provided by this service.
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Location |
New York, New York |
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Chief, Clinical Genetics Service |
Kenneth Offit, MD, MPH |
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Schedule Appointments |
212.434.5149 |
Memorial Sloan-Kettering provides a full range of genetic counseling, testing, screening, and research. The following sets out the components of the comprehensive genetic testing program.
Community and Physician Awareness |
MSKCC sponsors yearly courses in human genetics. |
Education |
Staff speak at Post Treatment Resources and other client education sessions. |
Identify Eligible Clients/Referral |
Genetic counseling appointments can be arranged by the family physician or by the client by calling 212.639.5149. |
Pre-test Counseling and Risk Assessment |
Cancer risk assessment and individualized cancer screening recommendations are available through the Clinical Genetics Service. Counseling about increased risk of cancer is available, either by referral from the Wellness Program, by direct physician referral, or by self-referral. Memorial Sloan-Kettering Cancer Prevention and Wellness Program also offers screening tests and counseling services to help people prevent cancer or detect it early. Each client meets one-on-one with a wellness specialist who discusses his or her health, family history, and lifestyle and then works with the client to design a personal program. Clients complete a detailed questionnaire to evaluate the family history and current health status. Based on the results of the questionnaire and a personal consultation, the wellness specialist determines what screening tests the client needs and what other counseling may be appropriate. |
Informed Consent Procedures |
As required by New York State law, informed consent is extensive, involving education on risks, benefits, and options to genetic testing. |
Confidentiality Standards |
As required by New York State law, written permission is required to release test results from confidential research records. |
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Testing |
Because of special requirements of New York State, Memorial Sloan-Kettering Cancer Center offers commercial testing by laboratories that are certified by the New York State Department of Health. |
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Available Testing at or Through Memorial Sloan-Kettering Cancer Center |
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Laboratory Quality Assurance |
For BRCA and HNPCC testing, the laboratory is approved by the New York State Department of Health. Other testing is performed by reference laboratories. |
Post-Test Counseling |
Current and future genetic testing may require information from many family members. Memorial Sloan-Kettering's Clinical Genetics Service provides assistance in obtaining this information, which includes official documentation of the medical history of the family. Full explanation of implications of test results and options for cancer prevention and early detection are provided. |
Cancer Screening |
The Clinical Genetics Service also provides individualized guidelines on cancer screening that are appropriate to each client's level of risk. Screening for cancers of the breast, cervix, prostate, colon, and skin are available. |
Medical and Surgical Management |
Referrals are coordinated with appropriate specialists. |
Psychological and Supportive Services |
A psychologist is available for consultations, and referrals to psychiatrists, support groups, and grief counselors are available. |
Memorial Sloan-Kettering Cancer Center is a leader in genetic research and encourages clients to participate in the various types of research. For example, the center has a research interest in hereditary hematologic cancers, and has a number of peer-reviewed research studies that provide genetic testing at no cost to individuals who qualify for these protocols.
Identifying New Genes |
Active research is underway to identify new genes predisposing to cancers of the colon, breast, lymphoma, and other malignancies. |
Improving Counseling Methods |
Two peer-reviewed grants are studying issues on improving counseling methods, including a study of internet-enabled informed consent. |
Improving Testing Methods |
MSKCC pinpointed that just three mutations in BRAC1 & BRCA2 account for most hereditary breast and ovarian cancer in people of Ashkenazi descent. |
Implementing Chemoprevention Trials |
We refer patients for the STAR trial and are developing other approaches. |
Discovering Clinical Treatments for Genetic Disorders |
Investigators are studying how to manipulate certain genes to make cancer therapies more effective. |
Tracking Long-Term Results |
Virtually all clients tested at MSKCC participate in long-term follow-up studies, with a special focus on the impact of surveillance and preventive surgery. |
Quality Assurance |
The Service participates in quarterly QA as a clinical service of the hospital. |
Training |
The Clinical Genetics Service at Memorial Sloan-Kettering Cancer Center has a post-doctoral laboratory fellow and post-doctoral clinical fellow, as well as genetic counseling interns rotating from the graduate program at Sarah Lawrence College. |
Last updated: 2/20/2008
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NCCN 1st Annual Forum: Innovative Diagnostics & Therapeutics in Cancer Care™ |
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